Tuesday, September 27th, 2022
3:30 PM - 4:30 PM
Jeremy Rotty, Ph.D.
Assistant Professor of Biochemistry and Molecular Biology
Uniformed Services University
Host: Ken Campellone
Join us at 3:15 in the BPB lobby for refreshments, Seminar begins at 3:30
"Context-dependent regulation of the actin cytoskeleton influences macrophage function”
Dr. Rotty obtained a Bachelor’s degree in biology from Berea College. He then completed his PhD in the lab of Dr. Pierre Coulombe at the Johns Hopkins School of Medicine. This work revealed a novel regulatory role for keratin intermediate filaments in Src kinase signaling and cell motility, which jumpstarted his career-long interest in cell migration and the cytoskeleton. Dr. Rotty then completed his postdoctoral training in Dr. James Bear’s lab at the University of North Carolina, Chapel Hill. His postdoctoral work revealed that the actin cytoskeleton is homeostatically regulated, and that the branched actin-polymerizing Arp2/3 complex is required for integrin-mediated extracellular sensing in macrophages. Since 2017, Dr. Rotty has been an assistant professor in the Department of Biochemistry at the Uniformed Services University where he continues to study cell migration, cytoskeletal regulation and extracellular matrix sensing.