Welcome to the Department of Molecular and Cell Biology
- Nyholm lab sequences genome of Hawaiian bobtail squid
Raising the Odds Against Viral Infection
Dr. Eric May (left) discusses virus research with students Prakar Bansal (standing) and Shaan Kamal (right)
(Sean Flynn/UConn Photo)- UConn ranks among the Top 25 public universities in the nation
— U.S. News & World Report America’s Best Colleges (2020) - 2020 MCB Graduate Recruitment
View more photos - Learn the story of the ants on the BPB building
Fall 2023 MCB PhD Application Deadline: November 15, 2022
- Students working in MCB 1200 'Virus Hunting' Laboratory
- The MCB PSM microbial sequencing, assembly, and annotation winter session module.
The mission of MCB is to understand fundamental biological processes at the molecular and cellular levels across all domains of life. We accomplish this through research, classroom teaching, and laboratory training directed at promoting the intellectual curiosity and critical thinking of individuals at all career levels including undergraduate and graduate students, post-doctoral fellows, research staff members, and faculty.
News
- New Publication for the Klassen LabFremin BJ, Bhatt AS, Kyrpides NC, Global Phage Small Open Reading Frame (GP-SmORF) Consortium* (*JL Klassen is a member of the GP-SmORF Consortium). 2022. Thousands of small, novel genes predicted in global phage genomes Cell Reports 39:110984 https://www.sciencedirect.com/science/article/pii/S2211124722007707Posted on June 27, 2022
- An Experimental Treatment Failed in Mice, and Researchers Did the Right Thing: They Published About ItThe knowledge could help steer scientists toward more promising approaches. UConn Professor of Molecular and Cell Biology David Goldhamer, Alexion Pharmaceuticals researcher Jeffrey Hunter, and colleagues worked for years to discover a potential antibody therapy for FOP using accurate genetic mouse models of the disease developed by the two groups. The idea was that the […]Posted on June 20, 2022
Graf Receives 2022 CLAS Faculty Mentoring Award
Joerg Graf has been awarded the CLAS 2022 Faculty Mentoring of Graduate Students Award. The Faculty Mentoring Awards recognize faculty who demonstrate exemplary support, encouragement, and the creation of opportunities to enrich the learning and professional development of others. Awards are given in three categories each year: mentoring of faculty, mentoring of graduate students, and […]Posted on May 25, 2022
- Congratulations MCB 2022 University ScholarsOpen to undergraduate students from all of the University's schools and colleges, the University Scholar Program allows students to design and pursue an in-depth research or creative project and to craft a learning plan that supports their interests and academic goals during their final three semesters. Each student is mentored by an advisory committee of […]Posted on May 16, 2022
- 2022 Excellence in Applied Genetics and Technology AwardRoshni Mehta has been awarded the 2022 Excellence in Applied Genetics and Technology Award. Each year UConn's Center for Applied Genetics and Technology of the College of Liberal Arts and Sciences sponsors the award that is given to an outstanding graduating senior who has conducted original research in applied genetics/genomics using an innovative technology or […]Posted on May 9, 2022
News Archive
Fall 2023 MCB PhD Application Deadline: November 15, 2022
Upcoming Events
-
Jul
8
MCB PhD Defense: Sean Pearson11:00am
MCB PhD Defense: Sean Pearson
Friday, July 8th, 2022
11:00 AM - 12:00 PM
Storrs Campus BPB 131
Oral Dissertation Defense for the Doctoral Degree of
Sean Pearson
B.S. Gettysburg College
Experimental Analysis of Genes Important for Amino Acid and Extracellular DNA Metabolism in Haloferax volcanii
Friday, July 8, 2022
11 am
BPB 131
Major Advisor: Dr. R. Thane Papke
Associate Advisor: Dr. J. Peter Gogarten
Associate Advisor: Dr. Jonathan Klassen
Associate Advisor: Dr. Spencer Nyholm
Associate Advisor: Dr. Daniel Gage
Livestream Link: https://www.kaltura.com/index.php/extwidget/preview/partner_id/2090521/uiconf_id/38934061/entry_id/1_rhfqxn3u/embed/dynamic
Copy of Dissertation: https://www.dropbox.com/scl/fi/zcoys786srd7zkqcbfndq/Pearson_DissertationP.docx?dl=0&rlkey=gfn9fz9wjsw4njth64dqqcr9aContact Information: sean.pearson@uconn.edu
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Aug
25
MCB Department Retreat10:00am
MCB Department Retreat
Thursday, August 25th, 2022
10:00 AM - 04:00 PM
Avery Point Campus Avery Point
This event will feature new faculty talk(s), lunch, beverages, posters, and social activities.Contact Information: Ashley.landon@uconn.edu
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Sep
27
MCB Seminar Series: Dr. Jeremy Rotty3:30pm
MCB Seminar Series: Dr. Jeremy Rotty
Tuesday, September 27th, 2022
03:30 PM - 04:30 PM
Storrs Campus BPB 130
Jeremy Rotty, Ph.D.
Assistant Professor of Biochemistry and Molecular Biology
Uniformed Services University
Host: Ken Campellone
Dr. Rotty obtained a Bachelor’s degree in biology from Berea College. He then completed his PhD in the lab of Dr. Pierre Coulombe at the Johns Hopkins School of Medicine. Dr. Rotty then completed his postdoctoral training in Dr. James Bear’s lab at the University of North
Carolina, Chapel Hill. Since 2017, Dr. Rotty has been an assistant
professor in the Department of Biochemistry at the Uniformed Services University where he studies macrophage and microglial cell migration, cytoskeletal regulation and extracellular matrix sensing.
To learn more about Dr Rotty and his research, view his publication at https://www.mdpi.com/2073-4409/11/11/1806 and visit his website at https://medschool.usuhs.edu/bio/research/rotty-labContact Information: ashley.landon@uconn.edu
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Oct
4
MCB Seminar Series: Dr. Will Ludington3:30pm
MCB Seminar Series: Dr. Will Ludington
Tuesday, October 4th, 2022
03:30 PM - 04:30 PM
Storrs Campus BPB 130
Will Ludington, PhD
Department of Embryology, Carnegie Institution for Science
Department of Biology, Johns Hopkins University
Host: Stacey Hanlon
"A physical niche regulates assembly of a multispecies gut microbiota in Drosophila"
A complex microbial community inhabits the human gut and affects health. Using a less-complex model in Drosophila, we are working on mechanisms of how the host regulates gut microbiome colonization.
Dr. Ludington began his career in field ecology and invasive species eradications before getting into biophysics and cell biology. His lab studies gut colonization by symbiotic bacteria at scales ranging from molecules to populations of flies.
To learn more about Dr. Ludington's research, view his publication at https://www.biorxiv.org/content/10.1101/2021.09.30.462663v1 and his website at https://emb.carnegiescience.edu/science/faculty/william-ludingtonContact Information: ashley.landon@uconn.edu
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Recent Publications
Thousands of small, novel genes predicted in global phage genomes
Cell Rep.
An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice.
J. Clin. Invest.
The Earth BioGenome Project 2020: Starting the clock
pnas
Pulse-field gradient nuclear magnetic resonance of protein translational diffusion from native to non-native states
Protein Sci
Simultaneous Single-Cell Genome and Transcriptome Sequencing of Termite Hindgut Protists Reveals Metabolic and Evolutionary Traits of Their Endosymbionts
mSphere
Effect of actinorhizal root exudates on the proteomes of Frankia soli NRRL B-16219, a strain colonizing the root tissues of its actinorhizal host via intercellular pathway.
Res. Microbiol.
A favorable path to domain separation in the orange carotenoid protein
Protein Sci.
18S rRNA gene amplicon sequencing combined with culture-based surveys of maize rhizosphere protists reveal dominant, plant-enriched and culturable community members.
Environ. Microbio. Rep.
NADH/NAD+ binding and linked tetrameric assembly of the oncogenic transcription factors CtBP1 and CtBP2.
FEBS Letters
Draft Genome of Janthinobacterium lividum ID1246, isolated from a rainbow trout hatchery biofilm
Microbiol. Resour. Announc.