Welcome to the Department of Molecular and Cell Biology
Nyholm lab sequences genome of Hawaiian bobtail squid
Raising the Odds Against Viral Infection
Dr. Eric May (left) discusses virus research with students Prakar Bansal (standing) and Shaan Kamal (right)
(Sean Flynn/UConn Photo)UConn ranks among the Top 25 public universities in the nation
— U.S. News & World Report America’s Best Colleges (2020)- Learn the story of the ants on the BPB building
- Students working in MCB 1200 'Virus Hunting' Laboratory
- The MCB PSM microbial sequencing, assembly, and annotation winter session module.
The mission of MCB is to understand fundamental biological processes at the molecular and cellular levels across all domains of life. We accomplish this through research, classroom teaching, and laboratory training directed at promoting the intellectual curiosity and critical thinking of individuals at all career levels including undergraduate and graduate students, post-doctoral fellows, research staff members, and faculty.
Fall 2023 MCB M.S. Applications being Accepted NOW! Deadline: February 15, 2023
News
- Maltz-Matyschysk, Graf, Lynes Receive NIH AwardMichele Maltz-Matyschsyk, Joerg Graf, and Michael Lynes recently received an NIH award to support their work to define biomarker signatures of Multisystem Inflammatory Syndrome in Children (MIS-C, an adverse effect of SARS-CoV2 infection). They will be working together with a consortium of other universities and research institutes in Connecticut and New York. Their work will measure multiple protein […]Posted on February 6, 2023
Alder Awarded Reinhard-Frank Foundation Grant
Nathan Alder, along with collaborator Doron Rapaport from the University of Tübingen (Germany), has received an award from the Reinhard-Frank Foundation for research on mitochondria-targeted bioactive compounds. Support from this foundation is designed to advance novel research that builds upon existing research strengths and promotes sustained partnership between participating institutions. The supported research will explore […]Posted on February 2, 2023
- May and Alder Receive Collaborative NIH Grant with Johns Hopkins UniversityNathan Alder and Eric May have been awarded an R01 grant from the NIH National Heart, Lung and Blood Institute (NHLBI) as co-investigators on a project led by Steve Claypool at the Johns Hopkins University School of Medicine. The project, entitled “An intimate and multifaceted partnership: cardiolipin and the mitochondrial ADP/ATP carrier” (R01HL165729), is a […]Posted on February 2, 2023
- Lee, Nyholm and Zweifach Receive SFF AwardsThe Office of the Vice President for Research provides financial support up to $2,000 to faculty across all disciplines, on a competitive basis, to promote, support, and enhance the research, scholarship and creative endeavors of faculty at UConn. The Scholarship Facilitation Fund (SFF) is designed to assist faculty in the initiation, completion, or advancement of […]Posted on January 31, 2023
- New Publication from the Campellone LabGenomic instability caused by Arp2/3 complex inactivation results in micronucleus biogenesis and cellular senescence. Haarer EL, Theodore CJ, Guo S, Frier RB, and Campellone KG. PLoS Genetics 2023. 19(1):e1010045. doi: 10.1371/journal.pgen.1010045.Posted on January 31, 2023
News Archive
Upcoming Events
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Feb
9
MCB Cell and Developmental Biology Journal Club12:30pm
MCB Cell and Developmental Biology Journal Club
Thursday, February 9th, 2023
12:30 PM - 01:30 PM
Storrs Campus BPB 401
This week in Cell and Developmental Biology Journal Club, Darren Ni will lead a discussion of "A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepi- topes targetable by immunotherapy” by Zhang et al., 2022.
https://mcb.uconn.edu/wp-content/uploads/sites/2341/2023/02/Zhang-et-al-2022.pdfContact Information: david.daggett@uconn.edu
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Feb
9
EEB Seminar: Mercedes Burns (University of Maryland, Baltimore County)3:30pm
EEB Seminar: Mercedes Burns (University of Maryland, Baltimore County)
Thursday, February 9th, 2023
03:30 PM - 04:30 PM
Storrs Campus BPB 130
Title: "Arachnid Evolution in Three Parts: Sex, Sequencing, and Stickiness"
https://burnslab.umbc.edu/Contact Information: Sarah Knutie
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Feb
10
MCB Dissertation Defense: Didem Ozcan Tezgin10:00am
MCB Dissertation Defense: Didem Ozcan Tezgin
Friday, February 10th, 2023
10:00 AM - 12:00 PM
Storrs Campus GN 20
Department of Molecular and Cell Biology
University of Connecticut
Announces the
Oral Dissertation Defense for the Doctoral Degree
Didem Ozcan Tezgin
B.S. & M.S. University of Connecticut
Evaluation of a potent antiproliferative and anti-inflammatory novel antifolate capable of evading cellular methotrexate resistance
Friday, February 10, 2023
10:00 AM
GN 20
Webex Link: https://uconn-cmr.webex.com/uconn-cmr/j.php?MTID=m5d143410a20c42aa1f57de65e8cf5513
Major Advisor: Dr. Charles Giardina
Associate Advisor: Dr. Dennis Wright
Associate Advisor: Dr. Michael Lynes
Associate Advisor: Dr. Andrew Wiemer
Associate Advisor: Dr. Lee Wright
Link to Dissertation
https://drive.google.com/file/d/1qSowyMWH_RX_zXORlPUK7o0-jfNWzGc-/view?usp=sharingContact Information: didem.ozcan@uconn.edu
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Feb
10
MCB Research in Progress Seminar: Corey Theodore12:20pm
MCB Research in Progress Seminar: Corey Theodore
Friday, February 10th, 2023
12:20 PM - 01:10 PM
Storrs Campus BPB 130
Corey Theodore, Campellone Lab
"Addressing Arp2/3 complex activities in autophagy"Contact Information: victoria.robinson@uconn.edu
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Feb
10
CANCELED - MCB Faculty Meeting1:30pm
CANCELED - MCB Faculty Meeting
Friday, February 10th, 2023
01:30 PM - 02:30 PM
Storrs Campus TLS 263
February Faculty Meeting has been canceled. Next meeting: March 3Contact Information: Maggie.mcdonnell@uconn.edu
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Recent Publications
Campellone Lab:
Genomic instability caused by Arp2/3 complex inactivation results in micronucleus biogenesis and cellular senescence.
PLos Genet.
Nyholm Lab:
"Failure To Launch": Development of a Reproductive Organ Linked to Symbiotic Bacteria
mBio
Gogarten Lab:
A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability
Structure
Giardina Lab:
Incorporation of 53BP1 into phase-separated bodies in cancer cells during aberrant mitosis
J Cell Sci
Hird Lab:
Multiomics Characterization of the Canada Goose Fecal Microbiome Reveals Selective Efficacy of Simulated Metagenomes.
Microbiol Spectr.
Hanlon Lab:
When it comes to genetics, cheaters do prosper
Chromosome Res
Graf Lab:
Draft Genome Sequence of Plesiomonas shigelloides MD22D9, Isolated from the Digestive Tract of Macrobdella decora
Microbiol Resour Announc.
Teschke Lab:
High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine
Sci Adv