• Not Only Adorable: Squid Open Up New Antimicrobial Drug Possibilities
    After starting an NSF-funded collaboration with Associate Professor of Pharmaceutical Sciences Marcy Balunas, Spencer Nyholm, associate professor in the Department of Molecular and Cell Biology,  began studying the squid’s specialized reproductive gland, called the accessory nidamental gland, whose function was until then the subject of speculation. Read full article in UConn Today
  • Jax Lab for Genomic Medicine Type 2 Diabetes and Metabolism Symposium Jax Lab for Genomic Medicine Type 2 Diabetes and Metabolism Symposium
    Convening top global experts on diabetes genomics and pathogenesis, the Type 2 Diabetes & Metabolism Symposium will take place on November 14 and 15, 2019 at The Jackson Laboratory for Genomic Medicine in Farmington, Conn. Where: The Jackson Laboratory for Genomic Medicine, Farmington CT When: November 14-15, 2019 This special symposium will be hosted by […]
  • Professor Barbara Mellone Awarded NIH award Professor Barbara Mellone Awarded NIH award
    MCB Associate Professor Barbara Mellone received a $2.6million R35-MIRA grant from the National Institute of Health to fund her research on an elusive yet vital chromosomal structure that all plant and animal share: the centromere. This five year grant will support research efforts to determine the contribution of DNA repeats and centromere chromatin to the […]

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Recent Publications

Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate.
Sci Rep

Molecular dynamics study of membrane permeabilization by wild-type and mutant lytic peptides from the non-enveloped Flock House virus, Biochimica et Biophysica Acta (BBA)
Science Direct

Shielding the next generation: symbiotic bacteria from a reproductive organ protect bobtail squid eggs from fungal fouling.

Diverse deep-sea anglerfishes share a genetically reduced luminous symbiont that is acquired from the environment.

Ambient pH alters the protein content of outer membrane vesicles, driving host development in a beneficial symbiosis.
Journal of Bacteriology

Persistent symbiont colonization leads to a maturation of hemocyte response in the Euprymna scolopes/Vibrio fischeri symbiosis.
Microbiology Open

Oligomerization of RIG-I and MDA5 2CARD Domains
Protein Science

NMR mapping of disordered segments for a viral scaffolding protein enclosed in a 23 MDa procapsid
Biolophysical J

Astaxanthin attenuates the increase in mitochondrial respiration during the activation of hepatic stellate cell
The Journal of Nutritional Biochemistry

Efomycins K and L from a Termite-associated Streptomyces sp. M56 and Their Putative Biosynthetic Origin.
Frontiers in Microbiology

Structural Basis of Protein Kinase R Autophosphorylation

Keeping it fresh
eLIFE Sciences

Of capsid structure and stability: The partnership between charged residues of E-loop and P-domain of the bacteriophage P22 coat protein.
Journal of Virology

A hydrophobic network: Intersubunit and intercapsomer interactions stabilizing the bacteriophage P22 capsid
Journal of Virology

Full list of publications