The mission of MCB is to understand fundamental biological processes at the molecular and cellular levels across all domains of life. We accomplish this through research, classroom teaching, and laboratory training directed at promoting the intellectual curiosity and critical thinking of individuals at all career levels including undergraduate and graduate students, post-doctoral fellows, research staff members, and faculty.
- Dr. Jelena Erceg receives R35 MIRA Award to Fund Research on Genome Folding and RegulationAssistant Professor Jelena Erceg (Department of Molecular and Cell Biology, CLAS & Institute for Systems Genomics, joint appointment also with the Department of Genetics and Genome Sciences, UConn Health) has received a prestigious R35 Maximizing Investigator’s Research Award (MIRA) for Early Stage Investigators from the National Institute of Health (NIH) and National Institute of General […]Posted on August 16, 2022
- New Publication from the Erceg LabFleck K, Raj R and Erceg J (2022), The 3D genome landscape: Diverse chromosomal interactions and their functional implications. Front. Cell Dev. Biol. 10:968145. doi: 10.3389/fcell.2022.968145Posted on August 11, 2022
- Associate Professor Jonathan Klassen Receives Funding from UConn’s Research Excellence Program (REP)The Office of the Vice President for Research (OVPR) announced that Dr. Klassen’s proposal entitled "Who is Protecting Whom? Defining Defensive Roles in a Multipartite Symbiosis" has been selected for funding of $50,000. The goal of the OVPR’s Research Excellence Program is to provide seed funding to fuel innovative research, scholarship and creative endeavors that […]Posted on August 9, 2022
- Alder, Alexandrescu, May Labs Publish Collaborative Study"Structure-activity relationships of mitochondria-targeted tetrapeptide pharmacological compounds" Wayne Mitchell, Jeffrey D Tamucci, Emery L Ng, Shaoyi Liu, Alexander V Birk, Hazel H Szeto, Eric R May, Andrei T Alexandrescu, Nathan N Alder https://doi.org/10.7554/eLife.75531Posted on August 3, 2022
- New Publication from the Goldhamer LabYamamoto, M., Stoessel, S. J., Yamamoto, S., and Goldhamer, D. J. (2022). Over-expression of wild-type ACVR1 in fibrodysplasia ossificans progressiva mice rescues perinatal lethality and inhibits heterotopic ossification. J. Bone Miner. Res. https://doi.org/10.1002/jbmr.4617Posted on August 1, 2022
Fall 2023 MCB PhD Application Deadline: November 15, 2022
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The 3D genome landscape: Diverse chromosomal interactions and their functional implications
Front. Cell Dev. Biol.
Structure-activity relationships of mitochondria-targeted tetrapeptide pharmacological compounds
Over-expression of wild-type ACVR1 in fibrodysplasia ossificans progressiva mice rescues perinatal lethality and inhibits heterotopic ossification
J. Bone Miner. Res.
Enrichment of Non-B-Form DNA at D. melanogaster Centromeres
Thousands of small, novel genes predicted in global phage genomes
An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice
J. Clin. Invest.
The Earth BioGenome Project 2020: Starting the clock
Pulse-field gradient nuclear magnetic resonance of protein translational diffusion from native to non-native states
Simultaneous Single-Cell Genome and Transcriptome Sequencing of Termite Hindgut Protists Reveals Metabolic and Evolutionary Traits of Their Endosymbionts