News
David Goldhamer awarded an NIH R01 grant for $2.2M to study Regulation of Satellite Cell Development, Programming and Differentiation by Myogenic FactorsNational Institute of Arthritis and Musculoskeletal and Skin Diseases has awarded David Goldhamer, Professor of Cell and Developmental Biology a $2.2 million, 5-year award to study Satellite cells. Satellite cells are responsible for the marked regenerative capacity of skeletal muscle. Although these stem cells were discovered more than 50 years ago, the molecular mechanisms that […]Posted on October 9, 2020
Two UConn MCB PSM Alumni FeaturedSamantha Holmes (M.S. Applied Genomics) and Courtney Gunter (M.S. Microbial Systems Analysis), have been published in the PSM Alumni and Graduation Chronicle, 2020 Issue. See their profiles in the 2020 PSM ChroniclePosted on October 7, 2020
Spencer Nyholm Receives Award as Part of the Symbiosis in Aquatic Systems InitiativeSpencer Nyholm is part of a team that received a $550,000 award from the Gordon and Betty Moore Foundation to develop new tools to study symbiotic relationships in the Hawaiian bobtail squid. The award is part of the Symbiosis in Aquatic Systems Initiative and is investing $19 million over the next three years to support […]Posted on October 7, 2020
Two MCB Researchers Receive UConn Funding for Covid 19 Related ResearchJames Cole and Rachel O'Neill among five UConn researchers awarded internal funding to support researchers who are using their expertise to find new solutions to address the Covid-10 pandemic The program will award up to $50,000 to recipients. Dr. James Cole received $43,439, Targeting the Endoribonuclease of Coronaviruses, Co-PIs: Mark Peczuh, Chemistry Dr. Rachel O'Neill was […]Posted on October 2, 2020
Dr. Benson Retires after 40 Years at UConnDavid R. Benson, Ph.D., Professor of Microbiology, retired on June 1 after more than 40 years at UConn. Dr. Benson’s distinguished career includes service as Head of the Molecular and Cell Biology Department from 2007-2012. During that time, he oversaw the expansion of the department personnel, doubled undergraduate course enrollment, built administrative protocols and brought […]Posted on August 31, 2020
Upcoming Events
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Oct
20
MCB Seminar Series: Shawna Reed3:30pm
MCB Seminar Series: Shawna Reed
Tuesday, October 20th, 2020
03:30 PM - 04:30 PM
Other Online
MCB Seminar Series
Shawna Reed, PhD
Assistant Professor of Biomedical Sciences
Quinnipiac University
Host: Ken Campellone
"Coxiella and the arms race between host and pathogen…"
Summary:
The bacterium Coxiella burnetii enters eukaryotic host cells uses at least 130 secreted bacterial proteins to modify the late endosome into an autolysosomal, highly fusogenic compartment, allowing massive bacterial replication while promoting host cell survival and inhibiting innate immune responses to infection. Using an insect larval model for multicellular infection, bacterial effectors which inhibit immune response, promote multicellular infection and modulate Coxiella vacuole formation were identified.
As a scientist, Dr. Reed is passionate about uncovering the molecular interactions between host cells and intracellular bacteria. She has studied Rickettsia and Listeria actin-based intracellular motility at UC Berkeley and Coxiella genetics and host interactions at Yale.
In her laboratory, she looks forward to creating research projects for undergraduates curious about intracellular pathogens, bacterial genetics, interactions with host immune sensing pathways, and how individual bacterial effector proteins might contribute to virulence by hijacking host cell functions.
To learn more about Dr Reed's work, view https://mbio.asm.org/content/7/4/e01127-16.long
and visit her website:
https://directory.qu.edu/Profile/188042
Seminar Link:
https://uconnvtc.webex.com/webappng/sites/uconnvtc/meeting/download/73b0482edc2d4296b538911b3923d6f4?siteurl=uconnvtc&MTID=mf888e1957a812a5c6b3968a2580b5f42 -
Oct
22
EEB Seminar: Paulo R. Guimarães Jr. (Univ. São Paulo)3:30pm
EEB Seminar: Paulo R. Guimarães Jr. (Univ. São Paulo)
Thursday, October 22nd, 2020
03:30 PM - 04:30 PM
Other online
The Structure of Ecological Networks Across Levels of Organization
(email carlos.garcia-robledo@uconn.edu for zoom link) -
Oct
22
MCB PSM Professional Development Seminar5:00pm
MCB PSM Professional Development Seminar
Thursday, October 22nd, 2020
05:00 PM - 06:00 PM
Storrs Campus Virtual
Andrew Hesse
Precision & Translational Genomics Professional
* Attendance is limited to MCB PSM, PM, and Ph.D. students -
Oct
23
MCB Research Seminar: Dostie and Wainman12:20pm
MCB Research Seminar: Dostie and Wainman
Friday, October 23rd, 2020
12:20 PM - 01:20 PM
Other Online
MCB Research Seminar
Kristen Dostie, Lynes Lab
“Good protein gone bad: extracellular metallothionein induces immune cell hyperactivation in pro-inflammatory microenvironments”
Lauren Wainman, Core Lab
“The Role of Enhancers in Chronic Lymphocytic Leukemia Predisposition”
Seminar Link: https://us.bbcollab.com/collab/ui/session/guest/0453116de50844fe86f3edee5f7c6cc4 -
Oct
23
MCB Faculty Meeting3:00pm
MCB Faculty Meeting
Friday, October 23rd, 2020
03:00 PM - 04:00 PM
Other WebEx
MCB Faculty Meeting -
Oct
24
NESS 2020: The 19th Annual North Eastern Structure Symposium9:00am
NESS 2020: The 19th Annual North Eastern Structure Symposium
Saturday, October 24th, 2020
09:00 AM - 03:00 PM
Storrs Campus Virtual
This year's focus will be on the Structural Biology of Host-Pathogen Interactions. The latest developments on the frontiers of the field will be covered in lectures by distinguished invited speakers. The symposium will also feature a poster-session for students and post-doctoral fellows. Several posters will be promoted to short talks and prizes will be awarded for the best posters.
Plenary Speaker:
Ian Wilson Scripps Research Institute
Speakers:
Gaya Amarasinghe Washington University
Jorge Galan Yale University
Alexei Korennykh Princeton University
Jason McLellan University of Texas
Alexei Savchenko University of Calgary
Sandra Weller UCONN Health
Organizers:
James Cole
Melissa Caimano
Abstract Submission:
Abstracts for poster and oral presentations will be accepted until October 14, 2020. Enter your abstract during the registration process. You will be notified if your abstract is accepted to be presented at the conference.
Registration Fees:
Regular Registration: $30.00
Trainee Registration (student/post-doc): $15.00
Registration Deadline: Friday, October 23, 2020 at 5:00PM EST
Register at
https://uconnuecs.cvent.com/events/ness-2020-biomolecular-design-and-structure-prediction/event-summary-bdf7734a76ea41658b046b19615cc170.aspx -
Oct
29
MCB PSM Professional Development Seminar5:00pm
MCB PSM Professional Development Seminar
Thursday, October 29th, 2020
05:00 PM - 06:00 PM
Storrs Campus Virtual
Jeff Heinzman
Clinical Trial Manager, Altasciences
* Attendance is limited to MCB PSM, PM, and Ph.D. students -
Oct
30
MCB Research Seminar: Patrick Grady12:20pm
MCB Research Seminar: Patrick Grady
Friday, October 30th, 2020
12:20 PM - 01:00 PM
Other Online
MCB Research Seminar
Patrick Grady, R. O'Neill Lab -
Nov
3
MCB Seminar Series: Dr. Wendy Mok3:30pm
MCB Seminar Series: Dr. Wendy Mok
Tuesday, November 3rd, 2020
03:30 PM - 04:30 PM
Other Online
MCB Seminar Series:
Wendy Mok, Assistant Professor, Dept. of Molecular Biology & Biophysics, UCONN Health
Host: Victoria Robinson
"Bacteria in Sickness: How Persisters Recover from Antibiotic Treatment"
Summary: Depending on their metabolic state, bacteria may not necessarily die during antibiotic treatment. In this talk, I will discuss our work on investigating the environmental signals and molecular events that influence bacterial death and persistence following antimicrobial therapy.
Seminar Link:
https://uconnvtc.webex.com/webappng/sites/uconnvtc/meeting/download/73b0482edc2d4296b538911b3923d6f4?siteurl=uconnvtc&MTID=mf888e1957a812a5c6b3968a2580b5f42
Dr. Mok completed her Ph.D. with Dr. Yingfu Li at McMaster University in Hamilton, Ontario. Her doctoral thesis focused on bacterial toxin-antitoxin systems. This work sparked her interest in bacterial stress response and persistence, and this led her to complete her postdoctoral training in Dr. Mark Brynildsen’s lab in the Department of Chemical and Biological Engineering at Princeton University. At Princeton,she investigated the metabolic responses of bacterial persisters that enable them to overcome antibiotic treatment and contribute to infection relapse. In 2019,she joined MBB at UCONN Health, where research in her lab focuses on environmental triggers that impact persister formation and survival.
To learn more about Dr. Mok and her work, visit
https://www.pnas.org/content/115/27/E6301.short
and her website at:
https://health.uconn.edu/mok-lab/ -
Nov
5
MCB PSM Professional Development Seminar5:00pm
MCB PSM Professional Development Seminar
Thursday, November 5th, 2020
05:00 PM - 06:00 PM
Storrs Campus Virtual
Jennifer Wobrock
Scientist, Thermo Fisher
* Attendance is limited to MCB PSM, PM, and Ph.D. students
