Welcome to the Department of Molecular and Cell Biology
- Nyholm lab sequences genome of Hawaiian bobtail squid
Raising the Odds Against Viral Infection
Dr. Eric May (left) discusses virus research with students Prakar Bansal (standing) and Shaan Kamal (right)
(Sean Flynn/UConn Photo)- UConn ranks among the Top 25 public universities in the nation
— U.S. News & World Report America’s Best Colleges (2020) - 2020 MCB Graduate Recruitment
View more photos - Learn the story of the ants on the BPB building
Fall 2023 MCB PhD Application Deadline: November 15, 2022
- Students working in MCB 1200 'Virus Hunting' Laboratory
- The MCB PSM microbial sequencing, assembly, and annotation winter session module.
The mission of MCB is to understand fundamental biological processes at the molecular and cellular levels across all domains of life. We accomplish this through research, classroom teaching, and laboratory training directed at promoting the intellectual curiosity and critical thinking of individuals at all career levels including undergraduate and graduate students, post-doctoral fellows, research staff members, and faculty.
News
- Alder, Alexandrescu, May Labs Publish Collaborative Study"Structure-activity relationships of mitochondria-targeted tetrapeptide pharmacological compounds" Wayne Mitchell, Jeffrey D Tamucci, Emery L Ng, Shaoyi Liu, Alexander V Birk, Hazel H Szeto, Eric R May, Andrei T Alexandrescu, Nathan N Alder https://doi.org/10.7554/eLife.75531Posted on August 3, 2022
- New Publication from the Goldhamer LabYamamoto, M., Stoessel, S. J., Yamamoto, S., and Goldhamer, D. J. (2022). Over-expression of wild-type ACVR1 in fibrodysplasia ossificans progressiva mice rescues perinatal lethality and inhibits heterotopic ossification. J. Bone Miner. Res. https://doi.org/10.1002/jbmr.4617Posted on August 1, 2022
- Department of Molecular and Cell Biology Newsletter – Spring 2022View the latest edition of Expression, MCB's bi-annual newsletterPosted on July 28, 2022
- Mellone Lab Publishes New PaperVenkata S.P. Patchigolla, Barbara G. Mellone, Enrichment of Non-B-Form DNA at D. melanogaster Centromeres, Genome Biology and Evolution, Volume 14, Issue 5, May 2022, evac054, https://doi.org/10.1093/gbe/evac054Posted on July 18, 2022
- Inaugural MCB Department Head Distinguished Service AwardThe MCB Department is pleased to announce that the inaugural MCB Department Head Distinguished Service Award has been awarded to Katie Kyle for her efforts over the past few years on behalf of MCB. This award can be used to support research.Posted on July 11, 2022
News Archive
Fall 2023 MCB PhD Application Deadline: November 15, 2022
Upcoming Events
-
Aug
25
MCB Department Retreat10:00am
MCB Department Retreat
Thursday, August 25th, 2022
10:00 AM - 04:00 PM
Avery Point Campus Avery Point
This event will feature new faculty talk(s), lunch, beverages, posters, and social activities.Contact Information: Ashley.landon@uconn.edu
More -
Aug
30
MCB Seminar Series: Dr. Lawrence David3:30pm
MCB Seminar Series: Dr. Lawrence David
Tuesday, August 30th, 2022
03:30 PM - 04:30 PM
Storrs Campus BPB 130
Dr. Lawrence David
Associate Professor, Molecular Genetics & Microbiology, Duke University
Host: Kat Milligan-McClellan
"Nutrient limitation and the gut microbiome"
Summary: How does diet shape gut microbial ecology across mammals?
Bio: Dr. Lawrence David is an associate professor in Duke University’s Department of Molecular Genetics and Microbiology and Interim Director of the Duke Microbiome Center. The David Lab studies relationships between diet, the gut microbiome and human health. The lab is also interested in engineering new tools at the interface of nutrition and microbiology, including building genomic approaches for tracking food intake and microfluidic techniques for high-throughput assay of microbial metabolism. Lawrence was a Junior Fellow at the Harvard Society of Fellows, and he received a Ph.D. in Computational & Systems Biology from the Massachusetts Institute of Technology and a B.S. in Biomedical Engineering from Columbia University. Lawrence has been named one of the 10 Scientists under 40 years old to watch by ScienceNews and his work has been recognized with innovator and investigator awards from the Burroughs Wellcome Fund, the Searle Scholars Program, and the Arnold & Mabel Beckman, Hartwell, Alfred P. Sloan, and Damon Runyon Foundations.
To learn more about Dr. David and his work, view his publication https://www.nature.com/articles/s41564-018-0267-7 and visit his website at http://www.ladlab.org
Join us at 3:15 in the BPB lobby for refreshments, Seminar begins at 3:30
Livestream here: https://www.kaltura.com/index.php/extwidget/preview/partner_id/2090521/uiconf_id/38934061/entry_id/1_904uedgo/embed/dynamic?Contact Information: Ashley.landon@uconn.https://www.kaltura.com/index.php/extwidget/preview/partner_id/2090521/uiconf_id/38934061/entry_id/1_904uedgo/embed/dynamic?edu
More -
Sep
9
MCB Faculty Meeting1:30pm
MCB Faculty Meeting
Friday, September 9th, 2022
01:30 PM - 02:30 PM
Storrs Campus TLS 263
September Faculty MeetingContact Information: Maggie.mcdonnell@uconn.edu
More -
Sep
27
MCB Seminar Series: Dr. Jeremy Rotty3:30pm
MCB Seminar Series: Dr. Jeremy Rotty
Tuesday, September 27th, 2022
03:30 PM - 04:30 PM
Storrs Campus BPB 130
Jeremy Rotty, Ph.D.
Assistant Professor of Biochemistry and Molecular Biology
Uniformed Services University
Host: Ken Campellone
Join us at 3:15 in the BPB lobby for refreshments, Seminar begins at 3:30
Dr. Rotty obtained a Bachelor’s degree in biology from Berea College. He then completed his PhD in the lab of Dr. Pierre Coulombe at the Johns Hopkins School of Medicine. Dr. Rotty then completed his postdoctoral training in Dr. James Bear’s lab at the University of North
Carolina, Chapel Hill. Since 2017, Dr. Rotty has been an assistant
professor in the Department of Biochemistry at the Uniformed Services University where he studies macrophage and microglial cell migration, cytoskeletal regulation and extracellular matrix sensing.
To learn more about Dr Rotty and his research, view his publication at https://www.mdpi.com/2073-4409/11/11/1806 and visit his website at https://medschool.usuhs.edu/bio/research/rotty-labContact Information: ashley.landon@uconn.edu
More -
Oct
4
MCB Seminar Series: Dr. Will Ludington3:30pm
MCB Seminar Series: Dr. Will Ludington
Tuesday, October 4th, 2022
03:30 PM - 04:30 PM
Storrs Campus BPB 130
Will Ludington, PhD
Department of Embryology, Carnegie Institution for Science
Department of Biology, Johns Hopkins University
Host: Stacey Hanlon
Join us at 3:15 in the BPB lobby for refreshments, Seminar begins at 3:30
"A physical niche regulates assembly of a multispecies gut microbiota in Drosophila"
A complex microbial community inhabits the human gut and affects health. Using a less-complex model in Drosophila, we are working on mechanisms of how the host regulates gut microbiome colonization.
Dr. Ludington began his career in field ecology and invasive species eradications before getting into biophysics and cell biology. His lab studies gut colonization by symbiotic bacteria at scales ranging from molecules to populations of flies.
To learn more about Dr. Ludington's research, view his publication at https://www.biorxiv.org/content/10.1101/2021.09.30.462663v1 and his website at https://emb.carnegiescience.edu/science/faculty/william-ludingtonContact Information: ashley.landon@uconn.edu
More
Recent Publications
Structure-activity relationships of mitochondria-targeted tetrapeptide pharmacological compounds
eLife
Over-expression of wild-type ACVR1 in fibrodysplasia ossificans progressiva mice rescues perinatal lethality and inhibits heterotopic ossification
J. Bone Miner. Res.
Enrichment of Non-B-Form DNA at D. melanogaster Centromeres
GBE
Thousands of small, novel genes predicted in global phage genomes
Cell Rep.
An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice
J. Clin. Invest.
The Earth BioGenome Project 2020: Starting the clock
pnas
Pulse-field gradient nuclear magnetic resonance of protein translational diffusion from native to non-native states
Protein Sci
Simultaneous Single-Cell Genome and Transcriptome Sequencing of Termite Hindgut Protists Reveals Metabolic and Evolutionary Traits of Their Endosymbionts
mSphere