Nathan N. Alder, Associate Professor; Ph.D.: Biochemical and biophysical approaches to studying the structure, function, and biogenesis of membrane proteins; fluorescence-based investigation of membrane protein complexes and protein trafficking in mitochondria; membrane bioenergetics; organelle biogenesis. Alder Lab
Andrei T. Alexandrescu, Professor; Ph.D.: High-resolution solution NMR investigations of protein structure, folding, dynamics, and association; conserved physical properties of OB-fold proteins; amyloids; phage/virus and pathogen proteins. Alexandrescu Lab
Kenneth Campellone, Associate Professor; Ph.D.: My research goals are to determine (1) how the actin and microtubule cytoskeletons control the organization, shape, and movement of membranes in mammalian cells and (2) how cytoskeleton-driven membrane remodeling is altered during the pathogenesis of inherited and infectious diseases. A combination of genetic, biochemical, and cellular approaches are used to study these processes. Campellone Lab
Thomas T. Chen, Emeritus Professor; Ph.D.: Structure, evolution, regulation, and molecular actions of growth hormone and insulin-like growth factor genes; regulation of foreign genes in transgenic fish; development of model transgenic fish.
James Cole, Professor; Ph.D.: We use biochemical, biophysical and structural methods to define the key macromolecular interactions that regulate important biological processes. Our major focus is the innate immunity pathway for defense against viral infection. Cole Lab
Leighton Core, Assistant Professor; Ph.D.: The goal of our lab is to determine how changes in RNA transcription and processing drive changes or maintenance of cellular states during development or disease progression. Towards this goal, we primarily apply genomic techniques and bioinformatics to uncover the full transcriptional ‘signatures’ of various cell types as well as the fundamental mechanisms of transcription that underly them. Core Lab
Charles Giardina, Professor; Ph.D.: Studies of eukaryotic RNA polymerase II transcription regulation; mechanisms governing transcription of stress-response genes; the nature of RNA polymerase II interactions at the promoter. Giardina Lab
J. Peter Gogarten, Board of Trustees Distinguished Professor; Ph.D.: Origin and early evolution of cellular life; molecular evolution; horizontal gene transfer; diversity within microbial populations; selfish DNA; molecular parasites. Gogarten Lab
David J. Goldhamer, Professor; Ph.D.: Regulation of cell fates in mammalian development; transcriptional control and function of skeletal muscle regulatory genes; muscle stem cell function and plasticity; mechanism of heterotopic bone formation in human disease.
Joerg Graf, Professor and Associate Department Head for Graduate Research and Education; Ph.D.: Molecular genetics of bacteria-animal interactions; identification of bacterial genes required for host symbiosis; pathogenesis, evolution of virulence factors. Graf Lab
Jonathan Klassen, Associate Professor, Ph.D.: Microbial community ecology, especially using the fungus-growing ant symbiosis as a model system to study the evolution of microbial interaction networks; microbial natural product genomics, evolution and chemical ecology Klassen Lab
Juliet Lee, Associate Professor; Ph.D.: The regulation of cell movement; mechanochemical signal transduction; the role of intracellular calcium; cellular force production and its relationship to adhesion formation and cytoskeletal dynamics. Lee Lab
Michael A. Lynes, Professor and Department Head; Ph.D.: Genetic and biochemical control of the immune response; membrane structure and function during development; mechanisms of autoimmune dysfunction; multiplexed surface plasmon resonance imaging microarray assessments of biological signatures. Lynes Lab
Eric R. May, Associate Professor; Ph.D.: Computational and theoretical biophysics and biochemistry, with an emphasis towards understanding conformational/phase transitions and the mechanical and thermodynamic properties of biological materials. May Lab
Kat Milligan-Myhre, Assistant Professor, Ph.D. Our lab focuses on how host genetic background contributes to the balance between the immune response to microbiota in the gut and intestinal microbial membership. Milligan-Mhyre Lab
Kenneth M. Noll, Professor; Ph.D.: Biochemistry and molecular biology of thermophilic bacteria and archaebacteria; physiology of extremely thermophilic anaerobes; evolution of genome organization in prokaryotes. Noll Lab
Michael J. O’Neill, Associate Professor; Ph.D.: Molecular genetics of vertebrate development; molecular mechanisms of genomic imprinting; evolution of genomic imprinting; genetics of imprinting and behavior.
Rachel J. Waugh O’Neill, Professor; Ph.D.: Genetics of speciation; mammalian chromosome evolution; genome evolution and remodeling; transposable elements and retroelements; hybridogenesis and clonal inheritance in vertebrates; epigenetics. R.O’Neill Lab
R. Thane Papke, Professor; Ph.D.: Ecology and evolution of bacteria that live in extreme environments; community structure and function; bacterial species and speciation; comparative genomics; bacterial population genetics. Papke Lab
Carolyn M. Teschke; Professor and Associate Department Head for Undergraduate Research & Education; Ph.D.: In vivo and in vitro investigations of the assembly of virus capsids, the interactions between proteins and molecular chaperones, including those used in secretion of proteins from Mycobacterium species. Teschke Lab
Simon White, Assistant Professor; Ph.D.: Research in the White lab is focused on the mechanism of assembly of RNA viruses. In particular, the Picornaviridae encompass many important human and animal pathogens, such as polio, foot and mouth disease, and the common cold.
Ping Zhang, Associate Professor; Ph.D.: Drosophila chromosome structure and function; P element insertional mutagenesis; unusual transcriptional regulation of heterochromatin; Y chromosome genes required for spermatogenesis.
Adam Zweifach, Professor; Ph.D.: Lymphocyte physiology and cell biology; role of intracellular calcium dynamics in lymphocyte function; molecular mechanisms of exocytosis; signaling in the immune system. Zweifach Lab