Michel Geovanni Santiago-Martinez (Geo)

Assistant Professor

Molecular and Cell Biology / Microbiology

Education:

Postdoctoral Scholar, Microbiology and Biochemistry, Pennsylvania State University.

Ph.D., Microbiology, Universidad Nacional Autónoma de México (UNAM).

Research Interests: Our Microbial Ecophysiology Lab is focused on understanding the regulation of cellular processes in methanogenic and non-methanogenic archaea, and their actual role in free-living environments and host-associated microbiomes (animals and plants). Our team uses omics analysis combined with detailed functional characterization of proteins, cofactors, and metabolites to further our understanding of the ecophysiology of archaea, as well as their ability to interact with other organisms and survive under stress conditions.

Selected Publications:

1. Santiago-Martínez M.G., Sowers K., Ferry J.G. Carbonic anhydrase (Cam) supplies protons to the acetate symporter in acetotrophic methanogenesis in Methanosarcina acetivorans. Under review.
2. Santiago-Martinez, M.G., Spychalla, J., Miles, T. D., Crandall, S. G. The grape berry microbiome: untangling microbial community dynamics across varietals and vineyards. Under review.
3. Santiago-Martínez, M.G., Ferry J.G. Methods for culturing anaerobic microorganisms. Chapter for Methods in Molecular Biology. Edited by Dr. Emily Weinert.
4. Prakash D., Iyer P. R., Suharti S., Walters K. A., Santiago-Martínez M.G., Golbeck J. H., Murakami K. S., Ferry J. G. (2019). Structure and function of an unusual flavodoxin from the domain Archaea. Proc Natl Acad Sci USA. 116, 25917-25922. doi: 10.1073/pnas.1908578116.
5. Santiago-Martínez M.G., Marín-Hernández A., Gallardo-Pérez J.C., Yoval-Sánchez B., Feregrino-Mondragón R.D., Rodríguez-Zavala J.S., Pardo J.P., Moreno-Sánchez R., Jasso-Chávez R. (2019). FruBPase II and ADP-PFK1 are involved in the modulation of carbon flow in the metabolism of carbohydrates in Methanosarcina acetivorans. Biochem. Biophys., 669, 39-49. doi: 10.1016/j.abb.2019.05.012.
6. Santiago-Martínez M.G., Encalada R., Lira-Silva E., Pineda E., Gallardo-Pérez J.C., Reyes-García M.A., Saavedra E., Moreno-Sánchez R., Marín-Hernández A., Jasso-Chávez R. (2016). Regulation of glycogen synthesis/degradation and gluconeogenesis/glycolysis fluxes by the nutritional status in Methanosarcina acetivorans. FEBS J., 283, 1979-1999. doi: 10.1111/febs.13717.