MCB Undergrad Research Symposium – Submissions Now Being Accepted!

February 8, 2024

Submissions are now being accepted for the 2024 Undergraduate Research Symposium in Molecular and Cell Biology. Graduating senior MCB or Biophysics majors are encouraged to present their research project as a short 15 minute talk. Graduating Biology majors whose project is supervised by a MCB faculty member are also invited to present their work.

If you would like to participate, please e-mail the following information by Friday, March 29
to mcboffice@uconn.edu with
MCB Research Colloquium in the subject line.

Student Name:
Major:
Email:
Thesis/presentation Title:
Thesis Research Adviser:
Honors Adviser (if applicable):
Short bio and current research interests:
Availability: **Please provide time slots during which you have classes or labs that would conflict with your ability to participate. Even if you have no conflicts, please indicate this**

The top three MCB presentations will be selected for participation in the All-Biology Symposium and will be eligible for multiple awards.

The MCB Symposium will be held in two sessions. Session I, 4/9/2024 3:30 - 5:30 pm and Session II , 4/12 12:20 -2:00 pm.

NEW OPPORTUNITY! Undergraduate Education in Aging & Geroscience Research Program

February 6, 2024

New paid summer research opportunities at UConn or UConn Health - Education in Aging & Geroscience Research (EAGR) Program. To learn more about becoming an EAGR
Scholar, enrolling in geroscience coursework, and applying for funded summer research in labs at UConn and UConn Health, visit
 https://education-aging-geroscience.research.uconn.edu/ or contact kenneth.campellone@uconn.edu 

Sophomores & Juniors Apply Now! Deadline February 19, 2024

Dr. Pallavi Limaye Receives UConn Hartford Fellow Award

January 25, 2024

The University of Connecticut Department of Molecular and Cell Biology is delighted to announce that Dr. Pallavi Limaye has been selected as the inaugural UConn Hartford Teaching & Learning Equity Faculty Leadership Fellow to start in Spring 2024.

Read More

MCB Invites Applications for Summer Fellowships

January 18, 2024

Announcing the annual competition for our student summer fellowships in MCB. These distinguished fellowships are made possible by very generous donors and are offered on a competitive basis to the most highly qualified students in MCB.  Additional information about the named fellowships, including short biographies of those they are named in honor of can be viewed on the MCB website.

To facilitate the nomination, review and selection process, it is requested that nomination materials be submitted electronically as a single PDF to the Selection Committee at mcboffice@uconn.edu.  The application deadline for each award is February 12.

Please be mindful the Awards Committee is required to follow the fellowship indentures when considering nominations. Please pay close attention to the requirements of each fellowship as they vary and include examples where student research meets requirements along with dates of exams if applicable. The committee cannot consider any nominations which do not adhere to the requirements.

Claire M. Berg Graduate Fellowship in Genetics

Requirements are for a female graduate student in the field of study of genetics who has completed most course work requirements, made progress in her research, and been an active member in the University, local, regional or national scientific community. Nominations should include a one page letter of recommendation, transcript and a short CV.

Arthur Chovnick Graduate Fellowship in Genetics

Requirements are for a graduate student in the field of study of genetics who has completed most course work requirements, made progress in their research, and been an active member in the University, local, regional or national scientific community. Nominations should include a one page letter of recommendation, transcript and a short CV.

Richard C. Crain, Jr. Memorial Fellowship

Requirements are for a Ph.D. student in Molecular and Cell Biology who has completed three years of graduate studies with a minimum GPA of 3.2, demonstrated academic promise and has established research in the field of biochemistry. Nominations should include a one page letter of nomination including how the student's research meets the requirement for the award, a CV, current transcript and GPA.

Dr. Edward A. Khairallah and Dr. Lamia H. Khairallah Graduate Fellowship

Requirements are for a PhD student in Pharmacy or Molecular & Cell Biology who is producing promising research beyond the second year of study in the fields of Biochemistry, Cell Biology, or Toxicology. Preference will be given to candidates who best demonstrate the interests and talents of the late Drs. Edward A. and Lamia H. Khairallah through integration of the above disciplines in their dissertation research.  Interested applicants should submit:  (1) a brief letter of nomination from their major advisor, (2) a second letter of recommendation from another UConn faculty member, (3) a 2-page CV that includes a 250-word summary of their research project, and (4) a UConn (unofficial) grade transcript.

Jean Lucas-Lenard Special Summer Fellowship in Biochemistry

Requirements are for a graduate student actively pursuing research in gene expression, protein secretion, protein folding or membrane receptors and demonstrated academic promise. Nominations should include a one page letter of nomination including how the student's research meets the requirement for the award, a CV, current transcript and GPA.

 Jean Lucas-Lenard Special Summer Fellowship in Molecular and Cell Biology

Requirements are for a graduate student in Molecular and Cell Biology, actively pursuing (a) any aspect of COVID-19, be it immunology, therapeutics, inflammation, or (b) studying the microbiome, microchondrial diseases, and immunology in general along with exceptional academic promise. Nominations should include a one page letter of nomination and a CV, including current transcript and GPA.

Philip I. Marcus Graduate Student Fellowship in Virology

Requirements are for a graduate student in the field of virology doing research with animal viruses and/or interferon research. Nominations should include a one page letter of recommendation including how the student's research meets the requirement for the award, a CV, current transcript and GPA.

Pfizer Summer Fellowship in Molecular and Cell Biology

Requirements are for a student who has completed at least three years of graduate studies with a minimum GPA of 3.2 and demonstrated academic promise. Nominations should include a one page letter of nomination and a CV, including current transcript and GPA.

Antonio H. and Marjorie J. Romano Graduate Education Fellowship

Requirements are for a student pursuing a graduate program in microbiology. Nominations should include the advisor’s recommendation, a graduate transcript and current CV.

Cross-Disciplinary Fellowship in MCB and Pharmaceutical Sciences

A competitive fellowship to be awarded to a PhD student conducting dissertation research in either Pharmaceutical Sciences in the School of Pharmacy, or in the Department of Molecular and Cell Biology in CLAS. The student must have passed the general exam, demonstrated scientific promise, and contributed to the fundamental understanding of biological systems as evidenced by a record of publications and presentations. Priority will be given to students who are actively engaged in work that combines the interests of both departments.

Nominations should include a CV, a one-page letter of recommendation and the semester/year the student passed the qualifying examination. The awardee will be chosen by a joint awards sub-committee composed of two faculty members, one each appointed by their respective departments.  A student may receive the fellowship once during their tenure at UConn.

Biohaven Fellowship

A summer fellowship for an MCB PhD student conducting dissertation research in the Department of MCB and demonstrated academic promise. Nominations should include a CV and a one-page letter of recommendation. This will be an open award (no limitations on AOC) to be managed by the awards committee with our other fellowships. A student may receive the fellowship once during their tenure at UConn.

UNDERGRADUATE

 Todd M. Schuster Award in Molecular and Cell Biology

Requirements are for an undergraduate student pursuing an MCB major to provide an opportunity to have the practical experience of carrying out a research project developed in the laboratory of a faculty member of MCB. The student must have an established working relationship with a faculty member in MCB, demonstrate a deep interest in science, demonstrate academic promise, and be working on a project that involves the use of chemical and physical methods to investigate biological problems. Candidates whose research projects involve the use of whole animals directly or indirectly (as a source of materials used in experiments) will not be eligible for the award.

Nominations should include a CV, description of the proposed research project, that includes an explicit statement that no whole animals were involved with the research, student transcripts and a letter of recommendation from the student’s faculty research advisor.

NEW OPPORTUNITY! Undergraduate Education in Aging & Geroscience Research Program

December 7, 2023

New paid summer research opportunities at UConn or UConn Health - Education in Aging & Geroscience Research (EAGR) Program. To learn more about becoming an EAGR Scholar, enrolling in geroscience coursework, and applying for funded summer research in labs at UConn and UConn Health, visit https://education-aging-geroscience.research.uconn.edu/ or contact kenneth.campellone@uconn.edu 

Deadline January 31, 2024

MCB Seminar Series: Dr. Michael Church

December 5, 2023

Tuesday, December 5, 3:30 PM, BPB 130

Dr. Michael Church, Postdoctoral Research Associate, Stowers Institute for Medical Research

Host: Stacey Hanlon

Regulating metabolism through control of gene expression

Summary: Protein complexes that affect DNA accessibility by sliding/evicting nucleosomes are conserved throughout Eukarya, and play an important role in gene regulation. In the yeast Saccharomyces cerevisiae, one such complex, Swi-Snf, is a well-known activator of gene transcription. However, swi/snf mutants display elevated levels of metabolic gene transcription in contrast to its known role as an activator. We aimed to discover the reason for this phenomenon, and further investigate the relationship between metabolism, chromatin, and the proteins that influence both.

Bio: Dr. Church received both his  B.A. and Ph.D. from the Department of Microbiology at Trinity College Dublin, Ireland, after which he spent a short time working as an industrial scientist. Church moved to Kansas City, Missouri in 2017 to work as a Postdoctoral Research Associate in the lab of Jerry Workman, Ph.D. at the Stowers Institute for Medical Research. He is interested in how metabolism affects proteins that regulate gene expression, and vice versa.

Link to publication

MCB Seminar Series: Dr. Shaun Brinsmade

November 21, 2023

Tuesday, November 28, 2023, 3:30 PM, BPB 130

Dr. Shaun Brinsmade, Associate Professor, Department of Biology, Georgetown University

Host: Michel Giovani Santiago-Martinez

Integrating metabolism and virulence in Staphylococcus aureus

Summary: Metabolism fuels infection, and virulence can be thought of as a mechanism to maintain homeostasis. In my talk, I’ll discuss our current work to understand the linkages between bacterial physiology and the production of virulence factors in the model Gram-positive human pathogen Staphylococcus aureus.

About Dr. Brinsmade: Dr. Shaun Brinsmade earned his Bachelors of Science in Molecular and Cell Biology at the University of Connecticut. He was inspired in Dr. Teschke’s Biochemistry course to seek out undergraduate research in Dr. Judy Kelly’s lab. There he worked in the lab to help understand the structure, function, and catalytic mechanism of the D-ala-D-alacarboxypeptidase-transpeptidase. He then moved to the University of Wisconsin-Madison where he earned his PhD with Dr. Jorge Escalante-Semerena in the Dept. of Bacteriology to study bacterial physiology and Acetyl-CoA (Ac-CoA)homeostasis in the Gram-negative pathogen Salmonella enterica. Following his PhD studies, Dr. Brinsmade completed several years of postdoctoral work in the Dept. of Molecular Biology and Microbiology at Tufts Medical with Abraham “Linc” Sonenshein studying regulation of metabolism and virulence genes in Gram-positive bacteria. After training with Linc Sonenshein and a brief training at the ETH-Zürich with systems biologist Uwe Sauer, Dr. Brinsmade opened his own lab in August 2013. Thus, research in the Brinsmade Lab blends multiple fields and work from the last22 years and focuses on the physiological origins and molecular underpinnings of virulence in S. aureus. Dr.Brinsmade attributes his love (and passion!) for biochemistry, genetics, and microbiology in part to the UConn MCB faculty, including Drs Kelly, Knox, Teschke, Kendall, and Leadbetter.

Link to publications:

1.) https://pubmed.ncbi.nlm.nih.gov/36135382/ (relevant for my seminar)
2.) https://pubmed.ncbi.nlm.nih.gov/27116338/ (relevant for my seminar)
3.) https://pubmed.ncbi.nlm.nih.gov/12564922/ (where it all began…at UConn MCB)

Brinsmade website

Passing of Dr. Ken Doeg

November 13, 2023

Kenneth A. Doeg, 92, of Storrs Mansfield, CT passed away on November 5, 2023. He was born in West Hoboken, NJ, and graduated from Montclair Teacher's College in 1952. Ken DoegHe received his doctorate in biochemistry at Rutgers University in 1957 followed by postdoctoral work at the Enzyme Institute at the University of Wisconsin, Madison. In 1961 he moved to the University of Pennsylvania, Pittsburg, as an Assistant Professor, doing research on diabetes. In 1964 he accepted a position at UConn in the Biochemistry and Biophysics Section of the Biological Sciences Group, the common ancestor of the MCB, PNB, and EEB departments. His research dealt with the hormonal regulation of metabolism in mitochondria, biosynthesis and control of mitochondrial membrane synthesis, and the reconstitution of mitochondrial anion transporters. He also taught biochemistry and other biology courses. He retired as Professor of Molecular and Cell Biology in 1997.

Throughout his life Ken pursued many passions including opera, UConn basketball, and traveling around the world. He was a well-known AKC dog judge and was an active member of the South Windsor Kennel Club. After retirement, he volunteered at the Windham Hospital for over 25 years. He is survived by his two daughters, Beth Murana and Leslie Romero.

MCB Seminar Series: Dr. Victoria Jeffers

October 17, 2023

Dr. Victoria Jeffers, Assistant Professor of Microbial Pathogenesis in the Department of Molecular, Cellular and Biomedical Sciences, University of New Hampshire

Host: Aoife Heaslip

Placing a BET on bromodomains in Toxoplasma gondii

Read More

MCB Seminar Series: Dr. Binyam Mogessie

September 28, 2023

Dr. Binyam Mogessie,

Assistant Professor of Molecular, Cellular, and Developmental Biology, Yale

Assistant Professor of Obstetrics, Gynecology, and Reproductive Sciences, Yale

Wellcome Trust and Royal Society Sir Henry Dale Fellow

Host: Barbara Mellone

“Emerging mechanisms of chromosome segregation in mammalian eggs”

Read More