University of Connecticut
Department of Molecular & Cell Biology
91 North Eagleville Road, Unit 3125
Torrey Life Sciences 408
Storrs, CT 06269-3125
Telephone: 860-486-4257 or 860-486-4329
Education: Ph.D. Harvard University; Postdoctoral study, University of Massachusetts Medical Center
Research Interests: Cellular responses to environmental stress. Altered gene expression in animal cells responding to chemical and physical stress; analysis of regulatory signals, functions of induced proteins, physiologic significance of the responses. Effects of heat shock and chemical stress on chicken, mammalian, and fish cells.
House, S.D., Guidon, Jr., P.T , Perdrizet, G., Rewinski, M., Kyriakos, R., Bockman, R.S., Mistry T., Gallagher, P.A., and Hightower, L.E.. 2001. Effects of heat shock, stannous chloride, and gallium nitrate on the rat inflammatory response. Cell Stress Chaperones 6(2): 164-171.
Xiao, Chengfeng, Tangchun Wu, Aiming Ren, Qin Pan, Sheng Chen, Fen Wu, Xiaoying Li, Ruibo Wang, Lawrence E. Hightower and Robert M. Tanguay. 2003. Basal and inducible levels of Hsp70 in patients with acute heat illness induced during training. Cell Stress Chaperones 8(1): 86-92.
Kumar, R., G. Perdrizet, J. Enderle, M. Rewinski, M. Berman, and Hightower, L. 2004. Stress proteins are proinflammatory in vivo. Implications for bioengineers. IEEE Engineering in Medicine and Biology 23(3): 80-84.
P.H. Krone, S. R. Blechinger, T.G. Evans, J.A. Ryan, E.J. Noonan and L.E. Hightower. 2005. Use of Fish Liver PLHC-1 Cells and Zebrafish Embryos in Cytotoxicity Assays. Methods 35(2): 176-187.