Derek Laux

Visiting Assistant Professor

Molecular and Cell Biology

Education

• Postdoctoral Fellowship, University of Edinburgh, UK
• Ph.D., Molecular and Cellular Biology, University of Pittsburgh
• BA., Case Western Reserve University

Research Interests
My research focuses on the role of innate immune cells in the early tumor microenvironment, with particular interest in neutrophil behavior around preneoplastic cells and the role of senescent cells in immune cell recruitment.

Selected Publications

• Laux, D.W., Kelly, L., Ribeiro-Bravo, I., & Feng, Y. (2017). Live imaging the earliest host innate immune response to pre-neoplastic cells using a zebrafish inducible KalTA4-ERT2/UAS system. Methods in Molecular Biology, 138, 137–150.
• Ramezani, T., Laux, D.W., Ribeiro-Bravo, I., & Feng, Y. (2015). Live imaging of innate immune and transformed cell interactions by use of an inducible Gal4/UAS expression system in larval zebrafish skin. Journal of Visualized Experiments, (96).
• Laux, D.W., Young, S., Donovan, J.P., Mansfield, C.J., Upton, P.D., & Roman, B.L. (2013). Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent quiescence. Development, 140, 3403–3412.
• Laux, D.W., Febbo, J.A., & Roman, B.L. (2011). Dynamic analysis of BMP-responsive Smad activity in live zebrafish embryos. Developmental Dynamics, 240, 682–694.