Arlene Albert

Professor Emeritus

Molecular and Cell Biology

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Retired: 2017

Currently: Pre-Med Advisor, Pre-Med, UConn

Education: Ph.D. University of Virginia, 1978 (Biochemistry)

Research Interests: The effect of lipids on the structure and function of membrane proteins. Specifically, the structure of the G-protein receptor, rhodopsin, its interaction with lipids and the role which the lipid bilayer composition plays in modulating the biochemistry of visual signal transduction.

Selected Publications:
Albert A, Alexander D, Boesze-Battaglia K (2016). Cholesterol in the rod outer segment: A complex role in a “simple” system. Chem Phys Lipids 2016 Sep;199:94-105. doi: 10.1016/j.chemphyslip.2016.04.008.

“The bilayer enhances rhodopsin kinetic stability in bovine rod outer segment disk membranes.” Corley SC, Sprangers P, Albert AD. Biophys J. 2011 Jun 22; 100(12):2946-54. PMID: 21689528 [PubMed – in process]

“Assessment of bovine rod outer segment disk membrane heterogeneity utilizing flow cytometry.” Corley, SC, Albert AD. Exp Eye Res. 2011 Jan;92(1):20-7. Epub 2010 Nov 3. PMID: 2105540 2 [PubMed – indexed for MEDLINE]

“Photochemical and thermal stability of green and blue proteorhodopsins: implications for protein-based bioelectronic devices.” Ranaghan MJ, Shima S, Ramos L, Poulin DS, Whited G, Rajasekaran S, Stuart JA, Albert AD, Birge RR. J Phys Chem B. 2010 Nov 11;114(44):14064-70. PMID: 20964279 [PubMed – indexed for MEDLINE]

“Membrane protein fragments reveal both secondary and tertiary structure of membrane proteins.” Yeagle PL, Albert AD. Methods Mol Biol. 2010;654:283-301. PMID: 20665272 [PubMed – indexed for MEDLINE]

“Calorimetric studies of bovine rod outer segment disk membranes support a monomeric unit for both rhodopsin and opsin.” Edrington TC 5th, Bennett M, Albert AD.Biophys J. 2008 Sep 15;95(6):2859-66. Epub 2008 June 27. PMID: 18586850 [PubMed – indexed for MEDLINE] Free PMC Article

“G-protein coupled receptor structure.” Yeagle PL, Albert AD. Biochim Biophys Acta. 2007 Apr;1768(4):808-24. Epub 2006 Oct 10. Review. PMID:17097603 [PubMed – indexed for MEDLINE]

“The role of cholesterol in rod outer segment membranes.” Albert AD, Boesze-Battaglia K. Prog Lipid Res. 2005 Mar-May;44(2-3):99-124. Epub 2005 Mar 9. Review. PMID: 15924998 [PubMed – indexed for MEDLINE]