University of Connecticut
Department of Molecular and Cell Biology
91 North Eagleville Road, Unit 3125
Storrs, CT 06269-3125
Education: Ph.D. in Chemistry, University of Massachusetts, Amherst
Research Interests: Terrence P. Tougas has been involved in analytical chemistry, quality control statistics and the development of pharmaceuticals for over 30 years. He has contributed to the development and regulatory approval of several pharmaceutical products including pulmonary (MDI, inhalation solutions and nasal sprays) and antiviral (solid oral , SEDDS) products.
Terrence Tougas, Adrian Goodey, Jolyon Mitchell, Lana Lyapustina, Gareth Hardwell (2016) A Comparison of the Performance of Efficient Data Analysis Versus Fine Particle Dose as Metrics for the Quality Control of Aerodynamic Particle Size Distributions of Orally Inhaled Pharmaceuticals. AAPS PharmSciTech. DOI: 10.1208/s12249-016-0508-0
Terrence Tougas, Jolyon Mitchell, Lana Lyapustina (2013) Good Cascade Impactor Practices, AIM and EDA for Orally Inhaled Products. Springer SBN: 978-1-4614-6295-8 (Print)
Terrence Tougas, Sara Abelaira, Chan Li, Jeff Song, Jane Li, John Mc Caffrey, Thomas Purdue, Fenghe Qiu, Franklin Swanek, Kenneth Cohen (2012) Best Practices for Drug Substance Stress and Stability Studies During Early-Stage Development Part I – Conducting Drug Substance Solid Stress to Support Phase Ia Clinical Trials. Journal of Pharmaceutical Innovation. DOI 10.1007/s12247-012- 9136-8,
Terrence Tougas, David Christopher, Patrick Forenzo, Lana Lyapustina, Dennis Sandell, Walt Stroup, Charles Ireland, Nate Patterson, Michelle Quinlan, James Schwenke (2012) On the Shelf Life of Pharmaceutical Products. AAPS PharmSciTech. DOI 10.1007/s12247-012- 9136-8.
Terrence Tougas, Dennis Sandell (2012) Quality Considerations in the Establishment of Specifications for Pharmaceuticals. Statistics for Biomedical Research. Vol. 4:2 , pp. 125-135, DOI: 10.1198/sbr.2010.10333.
Terrence Tougas, Jolyon Mitchell, Lana Lyapustina (2011) Non-impactor-Based Methods for Sizing of Aerosols Emitted from Orally Inhaled and Nasal Drug Products (OINDPs). AAPS PharmSciTech. DOI:10.1208/s12249-011- 9662-6.
Terrence P. Tougas, David Christopher, Jolyon P. Mitchell, Helen Strickland, Bruce Wyka, Mike Van Oort, and Svetlana Lyapustina (2009) Improved Quality Control Metrics for Cascade Impaction Measurements of Orally Inhaled Drug Products (OIPs). AAPS PharmSciTech DOI: 10.1208/s12249-009-9312-4